Upstream Process Development
Optimization of cultivation conditions is not just important, but critical for achieving maximum yield in protein expression.
By adjusting factors such as temperature, pH, and nutrient composition, we can tailor a cultivation process specifically designed to maximize production in your chosen mammalian cell line.
Beginning with small-scale experiments in tubes and shake-flasks, we methodically identify the most favorable expression conditions and can further test scalability utilizing single-use bioreactors.
Whether you are seeking to develop a new process, optimize an existing one, conduct confirmation runs, or engage in pre-clinical production, our expertise and resources are at your disposal.
Key capablities:
- Fed-batch Production
- Increase yields up to 2-fold
- 2x 1 L Single Use Bioreactors
- Media and process optimization
Building on our established upstream platform, we have now expanded our capabilities with the Ambr® 250 system to further accelerate process development.
Still Bioneer, Now even Faster
– With the Ambr®250 high-throughput bioreactor system
Hear from Christian Müller, PhD, Sr. Project Manager & Principal Scientist, and Alexandra Baer, PhD, R&D Manager, Mammalian Cell Line Development, as they explain how the Ambr® 250 enhances upstream development and de-risks scale-up for biologics production.
Contact us for a free consultation
Interested in learning how we can support your project or pipeline?
We´re always happy to chat.
For further information please contact Sr. Business Development Manager Ryan Polito on rpo@bioneer.dk or +4551443005
For further information please contact Sr. Business Development Manager Ryan Polito on rpo@bioneer.dk or +4551443005
