BIONi010-C
A well-characterized hiPSC line for disease modelling, gene editing, and drug discovery research.
BIONi010-C is a widely used human induced pluripotent stem cell (hiPSC) line developed by Bioneer to support disease modelling, gene editing, and drug discovery across a broad range of research areas.
Originally derived from human dermal fibroblasts and reprogrammed using a non-integrating episomal method, BIONi010-C has become a trusted starting point for both academic and industry research.
Its proven performance, extensive characterization, and availability of genetically modified derivatives make it a robust platform for advanced cellular model development, either used directly by researchers in their own studies or as a foundation for Bioneer-led disease modelling and gene editing services.
Why researchers choose BIONI010-C
- Extensively characterized
- Widely used in academia and industry
- Suitable for CRISPR-based engineering, genetically stable
- Proven track record in disease modelling
- Large collection of derivative lines available
Applications
- Neurodegenerative disease research
- Isogenic disease models
- Drug discovery
- Functional genomics
- Cell engineering
Scientific background
BIONi010-C is a human induced pluripotent stem cell (hiPSC) line generated from dermal fibroblasts obtained from a healthy male donor of Black African ethnicity.
Reprogramming was performed using a non-integrating episomal vector approach, enabling the generation of pluripotent cells without genomic integration of reprogramming factors.
The cell line was originally published under the name K3P53 in a study investigating transient p53 suppression during reprogramming of human fibroblasts. Read the study here.
Since its initial publication, BIONi010-C has been used extensively in disease modelling and cell engineering applications and has served as the foundation for numerous genetically modified derivatives.
Build your next model with BIONi010-C
Whether you're starting with the parental cell line or require a customised cellular model, Bioneer offers a range of services that can accelerate your research.
- →iPS Cell Reprogramming←
- →Gene Editing←
- →Cell Bank Maintenance←
- →QC Processes for Cell Lines←
- →Parkinson's Disease Models←
- →Alzheimer's Disease Models←
- →Neuroinflammation Models←
Ready to discuss your project?
Whether you are interested in using BIONi010-C directly or need support developing a customised cellular model, our scientific team can help identify the best approach for your research.
Contact us to discuss your project.
For further information please contact Business Development Manager Jacob Mathias Bech on jmb@bioneer.dk or +4523202576
For further information please contact Business Development Manager Jacob Mathias Bech on jmb@bioneer.dk or +4523202576
